CovidChloroV1, Main, Exploration, bibRecord, 000031

Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?

Identifieur interne : 000031 ( Main/Exploration ); précédent : 000030; suivant : 000032

Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?

Auteurs : Hülya Gamze Çelik [Turquie] ; Iran Keske [Turquie] ; Ülker Ener [Turquie] ; Müge Tekba [Turquie] ; Mahir Kapmaz [Turquie] ; Krü Taylan Ahin [Turquie] ; Asl Özy Ld R M [Turquie] ; Saide Aytekin [Turquie] ; Vedat Aytekin [Turquie] ; Önder Ergönül [Turquie]

Source :

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [ 1878-3511 ] ; 2021.

RBID : pubmed:33130195

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Azithromycine (administration et posologie), Femelle (MeSH), Grippe humaine (traitement médicamenteux), Humains (MeSH), Hydroxychloroquine (administration et posologie), Hydroxychloroquine (effets indésirables), Mâle (MeSH), Oséltamivir (effets indésirables), Oséltamivir (usage thérapeutique), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Syndrome du QT long (induit chimiquement), Électrocardiographie (effets des médicaments et des substances chimiques).
MESH :
- administration et posologie : Azithromycine, Hydroxychloroquine.
- effets des médicaments et des substances chimiques : Électrocardiographie.
- effets indésirables : Hydroxychloroquine, Oséltamivir.
- induit chimiquement : Syndrome du QT long.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Oséltamivir.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus.

English descriptors

KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Azithromycin (administration & dosage), COVID-19 (drug therapy), Electrocardiography (drug effects), Female (MeSH), Humans (MeSH), Hydroxychloroquine (administration & dosage), Hydroxychloroquine (adverse effects), Influenza, Human (drug therapy), Long QT Syndrome (chemically induced), Male (MeSH), Middle Aged (MeSH), Oseltamivir (adverse effects), Oseltamivir (therapeutic use), SARS-CoV-2 (MeSH).
MESH :
- chemical , administration & dosage : Azithromycin, Hydroxychloroquine.
- chemical , adverse effects : Hydroxychloroquine, Oseltamivir.
- chemically induced : Long QT Syndrome.
- drug effects : Electrocardiography.
- drug therapy : COVID-19, Influenza, Human.
- chemical , therapeutic use : Oseltamivir.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, SARS-CoV-2.

Abstract

The aim of this study was to describe the QTc prolongation and related adverse cardiac events during the administration of hydroxychloroquine (HCQ) and its combinations for the treatment of coronavirus disease 2019 (COVID-19). Hospitalized patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who received HCQ and had initial and follow-up electrocardiograms performed between March 10 and May 30, 2020 were included. Critical QTc prolongation was detected in 12% of the patients. On multivariate analysis, diabetes mellitus (odds ratio 5.8, 95% confidence interval 1.11-30.32, p = 0.037) and the use of oseltamivir (odds ratio 5.3, 95% confidence interval 1.02-28, p = 0.047) were found to be associated with critical QTc prolongation.

DOI: 10.1016/j.ijid.2020.10.080
PubMed: 33130195
PubMed Central: PMC7834514

Affiliations:

Turquie

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000915
to stream Main, to step Curation: 000915

Le document en format XML

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<front><div type="abstract" xml:lang="en">The aim of this study was to describe the QTc prolongation and related adverse cardiac events during the administration of hydroxychloroquine (HCQ) and its combinations for the treatment of coronavirus disease 2019 (COVID-19). Hospitalized patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who received HCQ and had initial and follow-up electrocardiograms performed between March 10 and May 30, 2020 were included. Critical QTc prolongation was detected in 12% of the patients. On multivariate analysis, diabetes mellitus (odds ratio 5.8, 95% confidence interval 1.11-30.32, p = 0.037) and the use of oseltamivir (odds ratio 5.3, 95% confidence interval 1.02-28, p = 0.047) were found to be associated with critical QTc prolongation.</div>
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<Abstract><AbstractText>The aim of this study was to describe the QTc prolongation and related adverse cardiac events during the administration of hydroxychloroquine (HCQ) and its combinations for the treatment of coronavirus disease 2019 (COVID-19). Hospitalized patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who received HCQ and had initial and follow-up electrocardiograms performed between March 10 and May 30, 2020 were included. Critical QTc prolongation was detected in 12% of the patients. On multivariate analysis, diabetes mellitus (odds ratio 5.8, 95% confidence interval 1.11-30.32, p = 0.037) and the use of oseltamivir (odds ratio 5.3, 95% confidence interval 1.02-28, p = 0.047) were found to be associated with critical QTc prolongation.</AbstractText>
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	Serveur d'exploration COVID et hydrochloroquine
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Serveur d'exploration COVID et hydrochloroquine

Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?

Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?

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